The series is the first set in the Cosmic Era. This series begins with the Bloody Valentine War between Earth and the colonies that is similar to the One Year War of the original Gundam series with certain traditional elements from Mobile Suit Gundam Wing and After War Gundam X such as the presence of five multicolored Gundam mobile suits and the threat of an apocalypse. On one side is the Earth Alliance, and on the opposite is the space colonies that form ZAFT (Zodiac Alliance of Freedom Treaty). Mankind is divided over human genetic engineering, with normal humans known as "Naturals" and the genetically altered humans known as "Coordinators". Like the original series, while ZAFT has a head start on mobile suit design, the Earth Alliance quickly catches up with its five prototype Gundams. With ZAFT having stolen four of the prototypes, young Coordinator Kira Yamato pilots the GAT-X105 Strike Gundam and is forced to fight his old friend Athrun Zala. Little do they know that there exist sinister forces working to bring about events that go far beyond their worst nightmares.